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Standardized remission criteria in schizophrenia.

J van Os¹, T Burns, R Cavallaro

¹Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands. j.vanos@sp.unimaas.nl

Acta Psychiatrica Scandinavica

|January 21, 2006

Summary

This study reviews a new definition of remission in schizophrenia, finding it viable for clinical practice and research. Standardized criteria can improve treatment expectations and outcomes.

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Area of Science:

Psychiatry
Clinical Psychology
Neuroscience

Background:

Schizophrenia research has primarily focused on deficit states.
Limited attention has been given to defining illness plasticity via symptomatic remission.

Purpose of the Study:

To review a recently proposed concept of remission in schizophrenia.
To assess the viability and implications of standardized remission criteria.

Main Methods:

Qualitative review of a proposed remission definition.
Analysis of its conceptual framework and clinical applicability.

Main Results:

The proposed remission definition is conceptually viable and implementable in clinical trials and practice.

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Acceptance of this definition can elevate treatment expectations and improve clinical status documentation.

Validated outcome measures based on remission will enhance clinical investigations and facilitate new studies on cognition and function.

Remission is a distinct concept from recovery.

Conclusions:

Standardized remission criteria offer significant opportunities for clinical practice, health services research, and clinical trials.
The adoption of these criteria can advance the understanding and management of schizophrenia.