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IV contrast selection for MDCT: current thoughts and practice

Pamela T Johnson1, Elliot K Fishman

  • 1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, 601 N Caroline St., Rm. 3251, Baltimore, MD 21287.

AJR. American Journal of Roentgenology
|January 21, 2006
PubMed
Abstract

Insights

Higher iodine concentrations (350 mg I/mL+) in MDCT may enhance visualization of small abdominal arteries. However, for hypervascular tumors, higher concentrations may not improve tumor conspicuity.

Area of Science:

  • Radiology
  • Medical Imaging
  • Diagnostic Imaging

Background:

  • MDCT is crucial for body imaging.
  • Contrast concentration is a key factor in image quality.

Purpose of the Study:

  • Review studies on contrast concentration's effect on MDCT.
  • Report IV contrast protocols for MDCT angiography and abdominal tumors.

Main Methods:

  • Literature review of studies evaluating contrast concentration in MDCT.
  • Analysis of IV contrast infusion protocols.

Main Results:

  • Higher concentrations (≥350 mg I/mL) may improve visualization of small abdominal arteries.
  • Preliminary data suggest higher concentrations may not increase conspicuity in hypervascular HCC and pancreatic cancer.

Conclusions:

  • Optimizing contrast concentration is essential for MDCT.
  • Further research needed to determine optimal concentrations for specific applications.

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