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Co-Culture In Vitro Systems to Reproduce the Cancer-Immunity Cycle
Published on: June 7, 2024
Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards
Robbert G van der Most1, Andrew Currie, Bruce W S Robinson
1School of Medicine and Pharmacology and Western Australian Institute for Medical Research, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Perth 6009, Australia.
Abstract:
This review shows how tumor antigen cross-presentation is affected by the major therapeutic modalities including chemotherapy, radiotherapy, and surgery. We argue that this process could affect the way that a tumor works as its own cellular vaccine, and that it is differentially modulated by the choice of treatment.
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