Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Internal and cortical border-zone infarction: clinical and diffusion-weighted imaging features.

Seok Woo Yong1, Oh Young Bang, Phil Hyu Lee

  • 1Department of Neurology, School of Medicine, Ajou University, Suwon, South Korea.

Stroke
|January 21, 2006
PubMed
Summary

Internal border-zone (IBZ) and cortical border-zone (CBZ) infarcts have distinct causes and clinical outcomes. IBZ infarcts stem from hemodynamic compromise, while CBZ infarcts suggest embolic origins, impacting patient prognosis differently.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of intensive blood pressure lowering after endovascular thrombectomy with outcomes according to contrast staining ASPECTS.

Stroke and vascular neurology·2026
Same author

Endovascular thrombectomy in selected patients with active cancer and thrombocytopenia: outcomes under an institutional platelet transfusion practice.

Frontiers in neurology·2026
Same author

Development of a rapid and simple Xeno Nucleic Acid (XNA) sensor-based microRNA detection platform for Parkinson's disease diagnostics.

Journal of nanobiotechnology·2026
Same author

AI-Guided Patient-Derived Endothelial Modeling Identifies a Reversible Moyamoya-Specific miRNA Deficiency Corrected by Stem Cell-Extracellular Vesicles.

Translational stroke research·2026
Same author

Impact of Low-Density Lipoprotein Cholesterol Levels on Atherosclerotic Vascular Changes: Analysis of Korean Treat Stroke to Target Trial.

Journal of stroke·2026
Same author

Intensive Versus Conventional Blood Pressure Lowering After Successful Endovascular Thrombectomy: OPTIMAL-BP 1-Year Outcomes.

Stroke·2026

Area of Science:

  • Neurology
  • Neuroscience
  • Vascular Neurology

Background:

  • The precise pathogenesis of internal border-zone (IBZ) and cortical border-zone (CBZ) infarcts remains unclear.
  • Previous studies often combined these infarct types, leading to conflicting results regarding their underlying mechanisms and clinical implications.

Purpose of the Study:

  • To investigate and differentiate the pathogenic mechanisms of IBZ and CBZ infarcts.
  • To compare the clinical courses and neuroradiological features of patients with IBZ versus CBZ infarcts.

Main Methods:

  • Retrospective review of 946 patients with ischemic stroke in the middle cerebral artery territory.
  • Identification of IBZ and CBZ infarcts using diffusion-weighted imaging templates.
  • Comparison of baseline characteristics, clinical progression, and neuroimaging findings between IBZ and CBZ infarct groups.

Related Experiment Videos

Main Results:

  • IBZ infarcts were associated with higher rates of middle cerebral or internal carotid artery stenosis/occlusion and a rosary-like infarction pattern.
  • CBZ infarcts showed a higher frequency of concomitant small cortical infarcts.
  • Patients with IBZ infarcts experienced more frequent clinical deterioration and poorer outcomes at 3 months compared to CBZ infarct patients.

Conclusions:

  • IBZ infarcts are primarily attributed to hemodynamic compromise, whereas CBZ infarcts likely result from embolic events.
  • IBZ infarct patients exhibit worse early and late clinical courses.
  • Distinct therapeutic strategies may be necessary for managing IBZ and CBZ infarcts to mitigate clinical deterioration.