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Preparation of Primary Myogenic Precursor Cell/Myoblast Cultures from Basal Vertebrate Lineages
Published on: April 30, 2014
Microsatellite polymorphism in intron 1 of the bovine myostatin gene
Xochitl F De la Rosa-Reyna1, Mario A Rodríguez Pérez, Ana M Sifuentes-Rincón
1Laboratorio de Biotecnología Animal I, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Boulevard del Maestro esq. Elías Pińa, Col. Narciso Mendoza, Cd. Reynosa, Tam. C.P. 88710, México.
Abstract:
Microsatellites within genes have become important because of their association with genetic diseases in humans. A novel microsatellite was identified in the first intron of the bovine myostatin gene. It is characterized by a mononucleotide core motif that exhibits polymorphic sequence variants (from 12 to 21 repeats) within and between some bovine breeds. Structural analysis of the microsatellite region in bovines as well as in closely related species permitted to trace the possible mechanisms for its structural evolution across the order Artiodactyla.
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