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Thyrotoxicosis co-existing with ulcerative colitis.

Santhichandra Pai¹, Rajiv Mehta, Ganapathi Rao

¹Department of Internal Medicine,Amrita Institute of Medical Sciences, Amrita Lane, Elamakkara P O, Cochin 682 026, India. drsantheendu@yahoo.com

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology

|January 21, 2006

Summary

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A patient with ulcerative colitis experienced gastrointestinal issues that improved only after her thyrotoxicosis was managed. Controlling thyroid dysfunction was key to treating her inflammatory bowel disease effectively.

Area of Science:

Endocrinology
Gastroenterology

Background:

Thyrotoxicosis, a condition of excess thyroid hormones, can present with diverse symptoms.
Ulcerative colitis is a chronic inflammatory bowel disease affecting the colon.

Observation:

A 32-year-old female presented with severe gastrointestinal symptoms including vomiting, bloody diarrhea, and tenesmus.
She had a long-standing neck swelling and recent onset of thyrotoxicosis symptoms.

Findings:

The patient's ulcerative colitis symptoms were refractory to standard treatment (balsalazide).
Thyroid hormone levels were normalized using carbimazole, after which balsalazide became effective.

Implications:

This case highlights the critical interplay between thyroid status and gastrointestinal disease management.

Related Experiment Videos

Effective control of hyperthyroidism may be essential for successful treatment of inflammatory bowel disease in some patients.