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[Suspicion of metastases in laryngeal carcinomas]
F Esteban1, J M González-Pérez, J P Benaixa
1Servicio de Otorrinolaringología, Hospitales Universitarios Virgen del Rocío de Sevilla.
Objective:
To look for models predicting metastasis in laryngeal/hypopharyngeal carcinomas.
Design:
Prospective study.
Patients:
Sixty patients bearing laryngeal squamous cell carcinoma who were treated with curative purposes were followed prospectively with at least 10-year follow-up.
Parameters:
Clinical (Staging, site, age, alcohol and smoking intake, surgery on the primary tumor, neck surgery) and pathological (size, number of metastatic lymph nodes, T and N staging, degree of differentiation, Jakobsson's and Glanz's scoring of malignancy, both scores in biopsies and surgical specimens) parameters were recorded in each case.
Methods:
A multivariate analysis was performed to find out those parameters independently related to presence of metastases.
Results:
The prospective study rendered tumor burden and Glanz's scoring from biopsies to be independently related with the presence of metastases.
Conclusions:
Malignancy grading systems must be included in laryngeal carcinoma patients' planning of neck treatment.
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