Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analysis of German package inserts.

J Fuchs1, M Hippius, M Schaefer

  • 1Institute of Clinical Pharmacology, Friedrich Schiller University Jena, Germany. jfuchs-jena@t-online.de

International Journal of Clinical Pharmacology and Therapeutics
|January 24, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis.

Nature·2025
Same author

Saturation of the compression of two interacting magnetized plasma toroids evidenced in the laboratory.

Nature communications·2024
Same author

Hybridization and reticulate evolution in Diphasiastrum (flat-branched clubmosses, Lycopodiaceae) - New data from the island of Taiwan and Vietnam.

Molecular phylogenetics and evolution·2024
Same author

A closer look to the timing of orchidopexy in undescended testes and adherence to the AWMF-guideline.

Pediatric surgery international·2024
Same author

Absolute calibration up to 20 MeV of an online readout CMOS system suitable to detect high-power lasers accelerated protons.

The Review of scientific instruments·2023
Same author

Dynamics of Nanosecond Laser Pulse Propagation and of Associated Instabilities in a Magnetized Underdense Plasma.

Physical review letters·2023
Same journal

Methotrexate and folic acid supplementation in rheumatoid arthritis: A Japanese claims database and 538,985 patients from April 2015 to November 2020.

International journal of clinical pharmacology and therapeutics·2026
Same journal

Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report.

International journal of clinical pharmacology and therapeutics·2026
Same journal

Recombinant human growth hormone in pediatric patients using the FAERS database: Safety profile and update for the period 2004 - 2024.

International journal of clinical pharmacology and therapeutics·2026
Same journal

The triple neuromodulatory-immunomodulatory axis.

International journal of clinical pharmacology and therapeutics·2026
Same journal

Novel intravenous human IVIG in patients with secondary immunodeficiency: Interim analysis of a multicenter, prospective, non-interventional study.

International journal of clinical pharmacology and therapeutics·2026
Same journal

Network meta-analysis of bisphosphonates in the treatment of bone metastases from breast cancer.

International journal of clinical pharmacology and therapeutics·2026
See all related articles

German drug package inserts often lack crucial information and are difficult to understand, impacting patient compliance and drug effectiveness. Optimization and patient testing are essential for safe and effective medication use.

Area of Science:

  • Pharmaceutical Sciences
  • Patient Education
  • Regulatory Affairs

Background:

  • Patient package inserts (PPIs) are vital for medication adherence and therapeutic outcomes.
  • Existing PPIs face ongoing criticism regarding readability and completeness despite regulatory efforts.

Purpose of the Study:

  • To evaluate the quality and suitability of German drug package inserts.
  • To identify specific deficiencies in information provision and readability.

Main Methods:

  • A comprehensive analysis of 68 German drug package inserts was conducted.
  • A predefined set of 104 quality criteria was used for the assessment.

Main Results:

  • Significant deficiencies were found, including missing daily maximum doses (73.5%) and drug interaction information (63.2%).

Related Experiment Videos

  • Storage instructions were inadequate in many cases (66.2%), and dosage instructions were often unclear or non-quantifiable (98.5%).
  • High rates of repetitive (97.1%), advertising (83.8%), and contradictory information (8.8%) were also noted.

    • Conclusions:

    • German drug package inserts require substantial optimization to improve clarity and comprehensiveness.
    • Pre-approval patient testing is recommended to ensure PPIs are understandable and prevent safety risks.