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Updated: Aug 13, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Right ventricular function after coronary surgery with or without bypass
Michel Durand1, Olivier Chavanon, Yannick Tessier
1Department of Anaesthesia, Grenoble University Hospital, Grenoble, France. MDurand@chu-grenoble.fr
Background And Objective:
Myocardial protection during aortic clamp period may sometimes be inadequate, especially for the right. The aim of this study was to compare right ventricle function after cardiac surgery with or without bypass.
Methods:
Patients undergoing multivessel coronary surgery with proximal severe right coronary lesion were included in a prospective observational cohort study including 29 patients undergoing coronary surgery with or without bypass. All patients were monitored with a pulmonary artery catheter with continuous right ventricular function. Right ventricular ejection fraction was measured at the arrival in ICU, 1, 3, 6, and 18 hours later.
Results:
The number of grafts that was higher in the bypass group (4.0 +/- 1.3) than in the off-pump group (2.6 +/- 0.6, p = 0.001). In the on-pump group, the right ventricular ejection fraction significantly decreased from 32.9 +/- 2.8 at arrival in ICU to 26.1 +/- 2.4, 6 hours later whereas in the off-pump group, it did not significantly change (32.4 +/- 1.8 to 31.9 +/- 2.3). Meanwhile, at the same time intervals, CVP was significantly lower in the off-pump group.
Conclusions:
In patients with severe right coronary stenosis, off-pump cardiac surgery seemed to provide better right ventricular protection.
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