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Updated: Aug 13, 2026
Cell Cycle-specific Measurement of γH2AX and Apoptosis After Genotoxic Stress by Flow Cytometry
Published on: September 1, 2019
Influence of endogenous glutathione level on X-ray induced cell cycle delay in human lymphocytes
1Genetics Laboratory, Department of Biotechnology and Bioinformatics, North-Eastern Hill University, Shillong, India.
Abstract:
Here, induction of chromosomal aberration after X-irradiation and the pattern of cell cycle kinetics have been investigated in human lymphocytes, after exogenous addition of reduced glutathione or by depleting levels of reduced glutathione endogenously. Involvement of cell cycle regulator proteins such as p53 and p21 has been investigated to elucidate their role in induction of delay in cell cycle progression after irradiation.
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