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Updated: Aug 13, 2026

Immunization of Alpacas (Lama pacos) with Protein Antigens and Production of Antigen-specific Single Domain Antibodies
Published on: January 26, 2019
Multicentric T-cell lymphosarcoma in an alpaca
N Pusterla1, K M Colegrove, P F Moore
1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. npusterla@ucdavis.edu
Abstract:
A two-year-old female alpaca with multicentric lymphosarcoma presented because of progressive weakness and recumbency. The diagnosis of lymphosarcoma was based on the detection of immature and atypical lymphocytes in a lumbosacral CSF sample. Post mortem examination confirmed multicentric lymphosarcoma involving multiple organs. Immunophenotyping using cross reactive T- and B-cell antibodies characterized the tumour as a T-cell lymphosarcoma.