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Multicentric T-cell lymphosarcoma in an alpaca.

N Pusterla1, K M Colegrove, P F Moore

  • 1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. npusterla@ucdavis.edu

Veterinary Journal (London, England : 1997)
|January 24, 2006
PubMed
Summary

A young alpaca diagnosed with multicentric lymphosarcoma showed progressive weakness. Diagnosis was confirmed via cerebrospinal fluid analysis, revealing T-cell lymphosarcoma in this animal cancer study.

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Area of Science:

  • Veterinary Oncology
  • Comparative Pathology

Background:

  • Multicentric lymphosarcoma is a significant neoplastic disease in animals.
  • Alpacas can be affected by various lymphoproliferative disorders.

Observation:

  • A two-year-old female alpaca presented with severe progressive weakness and recumbency.
  • Cerebrospinal fluid (CSF) analysis revealed immature and atypical lymphocytes.

Findings:

  • Post-mortem examination confirmed multicentric lymphosarcoma affecting multiple organs.
  • Immunophenotyping identified the tumor as a T-cell lymphosarcoma.

Implications:

  • This case highlights the diagnostic utility of CSF analysis in alpacas with suspected lymphosarcoma.
  • Understanding the immunophenotype is crucial for accurate diagnosis and potential therapeutic strategies in animal lymphoma.

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