Testatin transgenic and knockout mice exhibit normal sex-differentiation

Kouichi Hasegawa1, Shinichiro Chuma, Takashi Tada

  • 1Department of Development and Differentiation, Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara, Shogoin, Sakyo, Kyoto 606-8507, Japan. khase@frontier.kyoto-u.ac.jp

Summary

Testatin, a cystatin family member, is expressed in reproductive tissues. Its altered expression in mice did not impact fertility or sex differentiation, suggesting it is dispensable for these processes.