Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Rapid administration of crystalloid preload does not decrease the incidence of hypotension after spinal anaesthesia

C C Rout1, S S Akoojee, D A Rocke

  • 1Department of Anaesthetics, University of Natal.

British Journal of Anaesthesia
|April 1, 1992
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The research component of specialist registration--a question of alligators and swamps? A personal view.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2015
Same author

Review of policy and status of implementation of collaborative HIV-TB activities in 23 high-burden countries.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2014
Same author

The epidemiology of HIV infection in Morocco: systematic review and data synthesis.

International journal of STD & AIDS·2013
Same author

Has the quality of serosurveillance in low- and middle-income countries improved since the last HIV estimates round in 2007? Status and trends through 2009.

Sexually transmitted infections·2010
Same author

Oral mucosal lesions and HIV status in a rural household survey in South Africa.

SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging·2010
Same author

Comparison of adult HIV prevalence from national population-based surveys and antenatal clinic surveillance in countries with generalised epidemics: implications for calibrating surveillance data.

Sexually transmitted infections·2008

Rapid crystalloid fluid administration before spinal anesthesia for Cesarean section did not reduce hypotension. Faster fluid delivery increased central venous pressure, questioning the benefit of crystalloid preloading in this setting.

Area of Science:

  • Anesthesiology
  • Obstetrics
  • Cardiovascular Physiology

Background:

  • Spinal anesthesia for Cesarean section can cause hypotension.
  • Fluid preloading is a common strategy to mitigate this risk.
  • The optimal rate of fluid administration remains unclear.

Purpose of the Study:

  • To compare the effects of rapid versus conventional crystalloid preload rates on hypotension during spinal anesthesia for elective Cesarean section.
  • To assess the impact of preload rate on central venous pressure.

Main Methods:

  • Twenty parturients received either 20 ml/kg crystalloid over 10 minutes or 20 minutes before spinal anesthesia.
  • Systolic arterial pressure and central venous pressure were monitored.
  • Hypotension was defined as systolic arterial pressure <100 mm Hg and <80% of baseline.

Related Experiment Videos

Main Results:

  • Hypotension incidence was similar between groups (6/10 vs. 7/10 patients).
  • Both groups showed increased central venous pressure (P<0.05).
  • The 10-minute preload group had significantly higher central venous pressure (11.9 mmHg) compared to the 20-minute group (7.3 mmHg), with three cases of clinically unacceptable increases.

Conclusions:

  • Rapid crystalloid preload did not decrease hypotension incidence or severity.
  • Faster fluid administration led to a greater increase in central venous pressure.
  • The routine role of crystalloid preload before spinal anesthesia warrants further investigation.