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Decreased regurgitation with a soy formula containing added soy fiber
Karin M Ostrom1, Joan R Jacobs, Russell J Merritt
1Ross Products Division, Abbott Laboratories, Columbus, OH 43215-1724, USA.
Insights
Fiber-supplemented soy formula significantly reduced infant regurgitation compared to cow
Area of Science:
- Pediatrics
- Infant Nutrition
- Gastroenterology
Background:
- Regurgitation is a common issue in young infants.
- Cow's milk-based formula is a frequent cause of infant digestive discomfort.
- Alternative formulas are sought to manage common infant feeding problems.
Purpose of the Study:
- To evaluate the efficacy of fiber-supplemented soy formula in reducing infant regurgitation.
- To compare the incidence of regurgitation between soy and cow's milk-based formulas.
- To assess the nutritional adequacy and caloric distribution of fiber-supplemented soy formula.
Main Methods:
- A randomized controlled trial involving 179 infants.
- Infants were assigned to either cow's milk-based (CM) formula or soy formula with fiber (SF).
- Regurgitation incidence was recorded and compared between groups over 28 days.
Main Results:
- Initial daily regurgitation rates were similar between CM and SF groups.
- After 7 days, SF significantly reduced regurgitation episodes compared to CM (2.3 vs. 3.4 episodes, p=0.001).
- This reduction was sustained at 28 days, with 31% of SF feedings showing regurgitation versus 48% for CM (p=0.001).
Conclusions:
- Fiber-supplemented soy formula is effective in managing infant regurgitation.
- SF provides balanced nutrition without disrupting caloric distribution.
- This formula offers a viable alternative for infants experiencing digestive issues with standard formulas.
Abstract:
The objective of this randomized study was to determine if fiber-supplemented soy formula reduced regurgitation in young infants. We compared regurgitation in 179 infants randomly assigned cow's milk-based (CM, 90) formula or soy formula with fiber (SF, 89). Initial daily incidence was similar (CM, 3.6; SF, 3.9 episodes), but significantly lower after 7 days on SF (CM, 3.4; SF, 2.3; p = 0.001). Less frequent regurgitation after 7 days on SF was sustained after 28 days (CM, 48%; SF, 31% of feedings; p = 0.001). Feeding SF effectively managed regurgitation while providing balanced nutrition without altering caloric distribution as occurs with adding rice cereal to formula.
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