Related Experiment Video
Updated: Aug 8, 2026

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Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
A new technique of endoscopic full-thickness resection using a flexible stapler
G Kaehler1, R Grobholz, C Langner
1Department of Surgery, University Hospital Mannheim, Ruprechts-Karls-Universität Heidelberg, Germany. georg.kaehler@chir.ma.uni-heidelberg.de
Endoscopy
|January 24, 2006
Summary
Endoscopic full-thickness resection using a novel stapling device safely removed gastrointestinal lesions in two patients. This technique shows promise for treating gastric tumors, preserving the gastrointestinal wall integrity.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Endoscopic Procedures
Background:
- Existing endoscopic resection techniques are limited to the mucosal layer, posing challenges for deeper lesions.
- A safe and efficient method for endoluminal resection of gastrointestinal lesions is needed.
Observation:
- Two patients with early gastric cancer and a carcinoid tumor underwent endoscopic full-thickness resection.
- A flexible, intraluminal stapling device was utilized under gastroscopic control.
Findings:
- Gastric wall specimens up to 4 cm x 4 cm were successfully resected using the stapling device.
- Both procedures were uneventful, with uncomplicated patient recovery.
Implications:
- This endoscopic full-thickness resection technique offers a potential advancement in managing gastrointestinal neoplastic lesions.
- Further research is warranted to evaluate its broader applicability in diverse gastric conditions.

