Calvarial hyperostosis syndrome in two bullmastiffs

Area of Science:

• Veterinary Medicine
• Canine Pathology
• Radiology

Background:

• Calvarial hyperostosis syndrome (CHS) is a rare condition affecting bone growth.
• Previously documented cases of CHS in bullmastiffs have been exclusively in males.

Purpose of the Study:

• To describe the clinical, radiological, and magnetic resonance (MR) imaging features of calvarial hyperostosis syndrome in two female bullmastiffs.
• To report the first documented cases of CHS in female dogs of this breed.

Main Methods:

• Clinical examination and standard radiography were performed on two affected bullmastiffs.
• Magnetic resonance (MR) imaging was utilized in one case to assess intracranial and surrounding soft tissue structures.
• Radiographic findings of long bones were also evaluated.

Main Results:

• The two bullmastiffs were diagnosed with calvarial hyperostosis syndrome, representing the first reported instances in females.
• Clinical and radiographic presentations were consistent with previously reported male cases.
• MR imaging revealed frontal bone thickening, loss of normal fat signal, and adjacent soft tissue abnormalities.
• One dog exhibited long bone changes in the femora, similar to those observed in craniomandibular osteopathy.

Conclusions:

• Calvarial hyperostosis syndrome affects female bullmastiffs similarly to males.
• MR imaging provides valuable insights into the characteristic bone and soft tissue changes associated with CHS.
• The findings expand the understanding of CHS presentation and potential long bone involvement in canines.