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Updated: Aug 13, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
[Pediatric septic shock--timing, volume resuscitation and anticoagulation therapy]
Søren Kjaergaard1, Mathias Paul Goldinger, Anne Søe Højberg
1Anaestesisektor Nordjylland, Aalborg. kjaergaard@mail.tdcadsl.dk
Insights
Pediatric septic shock requires aggressive fluid resuscitation. This case highlights successful treatment of severe meningococcal septic shock in a child using aggressive volume resuscitation and anticoagulation therapy.
Area of Science:
- Pediatric critical care medicine
- Infectious diseases
- Pediatric emergency medicine
Background:
- Pediatric septic shock is a life-threatening condition characterized by severe hypovolemia.
- Aggressive volume resuscitation and goal-directed therapies have shown improved outcomes in pediatric septic shock.
- Meningococcal septic shock presents a significant challenge in pediatric critical care.
Observation:
- A 16-month-old child presented with severe meningococcal septic shock.
- The child experienced profound hypovolemia, a common feature of septic shock.
- The clinical presentation necessitated immediate and intensive management.
Findings:
- Aggressive volume resuscitation was initiated promptly.
- Anticoagulation therapy was administered alongside fluid resuscitation.
- The combined therapeutic approach led to a positive clinical response.
Implications:
- This case underscores the importance of early and aggressive fluid management in pediatric septic shock.
- The addition of anticoagulation may be beneficial in severe meningococcal septic shock cases.
- Further research into combined therapies for pediatric septic shock is warranted.
Abstract:
Pediatric septic shock is associated with severe hypovolemia, and children frequently respond well to aggressive volume resuscitation. In recent years, improved outcome has been reported when aggressive volume resuscitation and goal-directed therapies were applied to children with septic shock. We report a case of severe meningococcal septic shock in a child aged 16 months where aggressive volume resuscitation and anticoagulation therapy were applied.
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