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Related Experiment Videos

Colour-blindness and sensitivity to PTC in Hadza.

N A Barnicot1, J C Woodburn

  • 1Department of Anthropology, University College, London.

Annals of Human Biology
|January 1, 1975
PubMed
Summary

The Hadza people of Tanzania show high rates of red-green color blindness and phenylthiocarbamide (PTC) taste deficiency. These genetic traits were studied using Ishihara plates and PTC testing solutions.

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Area of Science:

  • Anthropology
  • Human Genetics
  • Population Studies

Background:

  • The Hadza are a hunter-gatherer population in Tanzania.
  • Understanding genetic diversity in isolated populations is crucial for evolutionary studies.

Purpose of the Study:

  • To investigate the prevalence of red-green color blindness and phenylthiocarbamide (PTC) taste deficiency in the Hadza population.
  • To compare these genetic traits with other African populations.

Main Methods:

  • Red-green color blindness was assessed using Ishihara non-numeral plates in 211 Hadza males.
  • PTC taste deficiency was evaluated in 118 individuals using a single solution and sorting test, with a follow-up detailed threshold test on 53 eastern Hadza males.

Main Results:

  • Three individuals were identified as protanopes, suggesting possible gene flow from an Isanzu ancestor.
  • Initial PTC testing revealed 22% of males and 27% of females as non-tasters.
  • Further analysis estimated 43% of eastern Hadza males as non-tasters, a high prevalence for an African population.

Conclusions:

  • The Hadza exhibit notable frequencies of red-green color blindness and PTC non-tasting.
  • These findings contribute to the understanding of genetic variation within African populations and potential evolutionary influences.

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