Polymorphic transformation of indomethacin under high pressures

Takehiro Okumura1, Masaya Ishida, Kozo Takayama

  • 1Technology Research & Development Center, Dainippon Sumitomo Pharma Co., Kasugade-naka, Konohana-ku, Osaka, Japan. takehiro-okumura@ds-pharma.co.jp

Summary

High pressure transforms indomethacin (IMC) forms. Stable alpha-IMC is readily prepared from amorphous IMC slurry under pressure, a novel method for polymorphic screening.

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