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Fungal infections of the genitourinary tract
Rana Traboulsi1, Zeina A Kanafani, Souha S Kanj
1Division of Infectious Diseases, American University of Beirut Medical Center, Beirut, Lebanon.
Abstract:
Fungal infections of the urinary tract are increasing in incidence, mostly because of the increasing use of antibacterial agents and indwelling urinary catheters. This review will focus mainly on the spectrum of genitourinary infections caused by Candida spp., including asymptomatic candiduria, cystitis, pyelonephritis, and renal candidiasis. Special emphasis will be placed on the therapeutic approach to the various clinical entities. Other fungal infections, such as urinary aspergillosis and cryptococcosis will be discussed briefly.
Insights
Urinary tract fungal infections, primarily Candida, are rising due to antibiotic and catheter use. This review details genitourinary fungal infections and their treatments.
Area of Science:
- Urology
- Infectious Diseases
- Mycology
Background:
- Increasing incidence of fungal urinary tract infections (UTIs).
- Association with antibacterial agent use and indwelling urinary catheters.
- Growing need for understanding and managing these infections.
Purpose of the Study:
- To review the spectrum of genitourinary infections caused by Candida species.
- To emphasize the therapeutic strategies for various clinical presentations.
- To briefly discuss other fungal UTIs like aspergillosis and cryptococcosis.
Main Methods:
- Literature review of fungal genitourinary infections.
- Focus on clinical entities and treatment approaches.
- Synthesis of current knowledge on Candida and other fungal UTIs.
Main Results:
- Candida species are the most common fungal pathogens in UTIs.
- Clinical manifestations range from asymptomatic candiduria to invasive renal candidiasis.
- Effective therapeutic strategies are crucial for successful management.
Conclusions:
- Fungal UTIs, particularly candiduria, require careful evaluation and management.
- Treatment selection depends on the clinical syndrome and patient factors.
- Awareness of emerging fungal pathogens is essential for urologists.
Related Concept Videos
Urinary Tract Infection I: Introduction
Candidiasis
Microbiota of the Urogenital Tract
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Trichomoniasis

