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Updated: Aug 13, 2026

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
Published on: April 25, 2016
Alternatives for measuring endogenous adrenocortical activity in asthmatics treated with inhaled corticosteroids
Larisa V Buyantseva1, Vernon M Chinchilli, Mark Tulchinsky
1Department of Medicine, Penn State College of Medicine, MC HO41, 500 University Drive, Milton S. Hersley Medical Center, Hershey, PA 17033, USA. Lara_buyantseva@hotmail.com
Abstract:
We compared a 12-hour, hourly integrated plasma cortisol profile in asthmatics treated with a corticosteroids with a variety of modified methods based on less frequent blood sampling. Excellent agreement with the reference was observed for sampling at 10 p.m. and 8 a.m. (correlation coefficient of 0.97; 95 % confidence interval 0.97, 0.98); at 9 p.m. and 7 a.m. (r = 0. 95; 0. 94, 0.96); at 11 p.m. and 7 a.m. (r = 0.94; 0.93, 0.95); every 2 hours (r = 0. 96; 0.96, 0.97); and every 3 hours (r = 0. 91, 0.91, 0.93). The two-sample alternatives (10 p.m/8 a.m. and 9 p.m/7 a.m.) are accurate, as well as more convenient, economical, and practical.
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