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One-step preparation of Hageman factor fragment concentrate
1Institute of Haematology and Blood Transfusion, Prague, Czechoslovakia.
Biomedical Chromatography : BMC
|July 1, 1992
Abstract:
The Hageman factor fragment (HFf) concentrate was prepared from acetone and dextran sulphate activated human plasma by chromatography on a CM-Sephadex column. The preparation was free of the main kallikrein inhibitors--Cl-inactivator, alpha 2-macroglobulin, antithrombin III and alpha 1-antitrypsin. The HFf concentrate can serve as an activator of prekallikrein in patient plasma.