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Factors influencing nerve regeneration in a trial of timcodar dimesylate
M Polydefkis1, M Sirdofsky, P Hauer
1Department of Neurology, The Johns Hopkins University, Baltimore, MD, USA. mpolyde@jhmi.edu
Neurology
|January 26, 2006
Abstract:
The authors assessed the ability of the neurophilin compound, timcodar dimesylate, to accelerate the return of epidermal nerve fiber density (ENFD) after a standardized nerve injury in a randomized double blind, placebo controlled trial. While there was no difference in the regeneration rate between the treatment and placebo arms, the baseline ENFD (p = 0.006), height (p = 0.02), and race (p = 0.03) were associated with the regeneration rate.

