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Updated: Jul 27, 2026

An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
Photodynamic therapy for superficial basal cell carcinoma and Bowen's disease
T H Clayton1, J Tait, C Whitehurst
1Department of Dermatology, Lancaster Royal Infirmary, UK. Tim.Clayton@leedsth.nhs.uk
Abstract:
Photodynamic therapy (PDT) is an effective treatment for superficial basal cell carcinoma (BCCs) and Bowen's disease. Several studies have reported complete response rates of 80-95% and an excellent cosmetic outcome. Bowen's disease and superficial basal cell carcinomas characteristically affect older patients who may also have associated difficulties with mobility. Using a portable PDT light source we were able to deliver PDT in a community setting with the aim of providing a more convenient service for patients. This randomised study confirmed that community delivered PDT is a viable treatment option and can be administered safely in the community by a trained dermatology nurse. The results from patient questionnaires suggest that community delivered PDT is more convenient to the patient, and also cost effective.
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