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Updated: Aug 13, 2026

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
Published on: April 18, 2025
[Correlation between positive lymph nodes and metastasis of colorectal cancer. Personal experience]
S Puleo1, O Zappalà, T R Portale
1Dipartimento di Scienze Chirurgiche, Trapianti d'Organo e Tecnologie Avanzate, Università degli Studi, Catania.
Abstract:
The authors, in a group of 190 patients treated with curative surgery for colorectal cancer, have studied the correlation between lymph nodes positive of primary tumor and rising of liver metastases. Even if the B2 stage nodes were negative, liver metastases were found in 6.25% of the patients probably due to an understaging; in C1 + C2 stage the rate of liver metastases was 28.1%, however in this group has not been demonstrated a statistical correlation with the number of positive nodes as a predictive negative prognostic factor.
