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Updated: Aug 10, 2026

Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells
Published on: February 21, 2014
[Hormone-dependence and C-ERBB2: relationship between estrogen receptor expression, estrogen-regulated proteins, and
L Costarelli1, F R Piro, L Fortunato
1UOC Anatomia e Istologia Patologica, Citologia Diagnostica, Genetica Medica, Azienda Ospedaliera S Giovanni-Addolorata-Calvary Hospital.
Abstract:
We reviewed 1491 consecutive cases of operated breast cancer between 1999-2004, and found that hormone-dependence, particularly if evaluated with functional markers of the estrogen receptor (estrogen regulated proteins, ERP), is inversely proportional to antigen neu expression. Our data confirms that ERP can give additional information on the probability of response to hormonal therapy.
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