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Tuberculosis in diabetic patients: a clinical perspective
V Nissapatorn1, I Kuppusamy, I Jamaiah
1Department of Parasitology, University of Malaya Medical Center, 50603 Kuala Lumpur, Malaysia. nissapat@hotmail.com
The Southeast Asian Journal of Tropical Medicine and Public Health
|January 28, 2006
Summary
Diabetic patients with tuberculosis (TB) are older and more likely male. Despite similarities in radiological findings, diabetics showed higher treatment success and lower treatment default rates for TB.
Area of Science:
- Medicine
- Public Health
- Infectious Diseases
Background:
- Tuberculosis (TB) disproportionately affects vulnerable populations.
- Diabetes mellitus is a growing global health concern, potentially impacting TB outcomes.
- Understanding the clinical profile of TB in diabetic patients is crucial for targeted interventions.
Purpose of the Study:
- To describe the clinical characteristics of tuberculosis in patients with diabetes mellitus (TBDM).
- To compare TBDM patients with non-diabetic TB patients regarding demographics, clinical presentation, and treatment outcomes.
Main Methods:
- Retrospective and descriptive study design.
- Inclusion of 1,651 patients diagnosed with tuberculosis.
- Comparison of demographic, clinical, radiological, and treatment data between TBDM and non-diabetic TB groups.
Main Results:
- TBDM patients were significantly older and had a higher male-to-female ratio compared to non-diabetic patients.
- Pulmonary tuberculosis was prevalent in 91.4% of TBDM patients, with no significant differences in radiological findings between groups.
- TBDM patients demonstrated higher treatment success rates (33.3%) and lower rates of treatment default (19.8%) and drug resistance (1.4%).
Conclusions:
- Diabetes is associated with older age and male predominance in tuberculosis patients.
- While radiological patterns are similar, TBDM patients may experience better treatment outcomes.
- Further research is warranted to explore the mechanisms behind improved treatment success in TBDM.
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