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[Acute femoral artery thrombosis after thrombin injection of a pseudoaneurysm]
H Wankmüller1, U Ganschow, A Schneider
1Klinik für Kardiologie, Pneumologie und Angiologie, Städtische Kliniken Esslingen.
Insights
A rare complication occurred after pseudoaneurysm treatment: thrombin displaced into the femoral artery, causing ischemia. Prompt intervention restored blood flow, with surgical repair of the pseudoaneurysm later proving successful.
Area of Science:
- Cardiology
- Vascular Surgery
- Interventional Radiology
Background:
- A 64-year-old woman presented with unstable angina pectoris and was treated with coronary stenting for two-vessel coronary disease.
- Following the procedure, a complex pseudoaneurysm developed at the right femoral artery access site, unresponsive to initial compression therapy.
Observation:
- A superficial hematoma was noted in the right groin.
- Percutaneous ultrasound-guided thrombin injection successfully thrombosed most of the pseudoaneurysm, but a small perfused area required further compression.
Findings:
- Thrombin leakage into the superficial femoral artery during compression led to acute critical limb ischemia.
- Immediate interventional recanalization and fibrinolysis restored arterial perfusion, resolving the pseudoaneurysm thrombosis.
Implications:
- This case highlights a rare complication of pseudoaneurysm treatment involving thrombin displacement.
- Successful management required a multi-modal approach including interventional and surgical techniques.
History:
A 64-year old woman was admitted because of unstable angina pectoris. The coronary angiogram revealed two-vessel coronary disease with predominantly subtotal stenosis of the right coronary artery, which was treated by primary coronary stenting. The post-interventional clinical course after closure of the right femoral artery was complicated by the development of a complex pseudoaneurysm: its ultrasound-guided compression was unsuccessful.
Investigations:
The clinical findings included a marked superficial hematoma in the right groin without any evidence of an abscess, confirmed by color duplex ultrasonography.
Treatment And Course:
24 hours later a successful percutaneous ultrasound-guided thrombin injection of the pseudoaneurysm was performed without any problems regarding the injection into the aneurysm. A small area within the aneurysm remained perfused and was treated by additional ultrasound-guided compression. A few minutes after the compression complete thrombosis of the right superficial femoral artery occurred with acute critical ischemia of the right leg, probably due to leakage of thrombin into the femoral artery at the sheath puncture. The immediate therapy, including interventional recanalization of the right femoral superficial artery and subsequent fibrinolysis, produced a complete reperfusion of the right femoral superficial and popliteal artery. The fibrinolytic therapy resolved the thrombosis of the pseudoaneurysm. The remainder of the perfused pseudoaneurysm was treated surgically after one week without problems.
Conclusion:
This case demonstrates a so far rarely published complication of the displacement of thrombin from an intervention ally treated pseudoaneurysm into the right superficial femoral artery through a broad compound channel after ultrasound-guided compression.
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