Related Experiment Video
Updated: Aug 13, 2026
10:26
RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Detection of human papillomavirus type 34 in Bowen's disease on the pubic area
1Department of Dermatology, Nihon University School of Medicine, Tokyo, Japan. hhara@med.nihon-u.ac.jp
Abstract:
We describe an 86-year-old man with Bowen's disease on the pubic area. The lesion was clinically a black-brownish keratotic nodule resembling seborrheic keratosis. Histopathological findings showed those of Bowen's disease and harboured human papillomavirus type 34 DNA. Genital, but not skin, human papillomaviruses are responsible for Bowen's disease on the skin.