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Proptosis: etiology and demographic patterns.

Muhammad Zubair Masud¹, Tariq Farooq Babar, Arshad Iqbal

¹Department of Ophthalmology, KIOMS and Hayatabad Medical Complex, Peshawar. zubairmasud@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|January 31, 2006

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Neoplasms are the leading cause of proptosis, a condition causing eye protrusion, in both children and adults. Early diagnosis and management are crucial to prevent vision loss.

Area of Science:

Ophthalmology
Ocular Oncology
Orbital Diseases

Background:

Proptosis, characterized by abnormal protrusion of the eyeball, can significantly impact vision and requires thorough etiological investigation.
Understanding the demographic patterns and causes of proptosis is essential for effective clinical management.

Purpose of the Study:

To investigate the demographic characteristics of patients presenting with proptosis.
To identify the primary causes and etiological patterns of proptosis in a specific patient cohort.

Main Methods:

A cross-sectional descriptive study was conducted.
Sixty patients with proptosis were evaluated through detailed history, clinical examinations, and investigations including radiological and histopathological assessments.
Patients were categorized into pediatric (0-15 years) and adult (>15 years) age groups.

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Main Results:

Neoplasms were the most frequent cause of proptosis (33%), followed by orbital inflammations (23%) and infections (20%).
Structural abnormalities accounted for 12%, vascular abnormalities for 7%, and trauma for 5% of cases.
Visual deterioration was observed in over half of the patients presenting with proptosis.

Conclusions:

Neoplasms represent the most common etiology of proptosis across both pediatric and adult populations.
Proptosis serves as a key indicator of underlying orbital pathology, often associated with significant visual impairment.
Prompt referral, accurate diagnosis, and timely intervention are vital to mitigate visual morbidity associated with proptosis.