Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

COPD exacerbations .1: Epidemiology.

G C Donaldson1, J A Wedzicha

  • 1Academic Unit of Respiratory Medicine, University College London, UK.

Thorax
|January 31, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global health impacts of ambient fine particulate pollution associated with climate variability.

Environment international·2024
Same author

Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD.

Respiratory research·2021
Same author

Changes in cold-related mortalities between 1995 and 2016 in South East England.

Public health·2019
Same author

Misspecification of at-risk periods and distributional assumptions in estimating COPD exacerbation rates: The resultant bias in treatment effect estimation.

Pharmaceutical statistics·2016
Same author

Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD.

Revista portuguesa de pneumologia·2015
Same author

Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations.

Respiratory medicine·2014
Same journal

Comparative performance of endobronchial ultrasound-guided sampling techniques in patients with mediastinal lesions: a network meta-analysis.

Thorax·2026
Same journal

Vitamin A and D impact on lung function: differential or common effects across the lifespan?

Thorax·2026
Same journal

The impact of vitamins A and D on lung function and regulatory epigenetics in adult and childhood asthma.

Thorax·2026
Same journal

Radiological factors associated with the recurrence of <i>Mycobacterium avium complex</i> pulmonary disease: a multicentre retrospective cohort study.

Thorax·2026
Same journal

Daughter vesicles in primary diaphragmatic hydatid cyst.

Thorax·2026
Same journal

Pulmonary monocyte kinetics in healthy volunteers and subjects with inflammatory arthritis.

Thorax·2026
See all related articles

This review examines chronic obstructive pulmonary disease (COPD) exacerbations, focusing on their frequency, timing, and impact on lung function decline and mortality. Understanding exacerbation patterns is crucial for managing COPD progression and patient outcomes.

Area of Science:

  • Pulmonology
  • Epidemiology

Background:

  • Chronic obstructive pulmonary disease (COPD) exacerbations significantly impact patient health and healthcare costs.
  • Understanding the epidemiology of COPD exacerbations is vital for effective disease management.

Purpose of the Study:

  • To review the epidemiology of COPD exacerbations.
  • To discuss the definition, frequency, time course, natural history, and seasonality of exacerbations.
  • To explore the relationship between exacerbations and lung function decline, disease severity, and mortality.

Main Methods:

  • Literature review of epidemiological studies on COPD exacerbations.
  • Analysis of data concerning exacerbation frequency, timing, and influencing factors.
  • Discussion of the distinction between recurrent and relapsed exacerbations.

Related Experiment Videos

Main Results:

  • Exacerbations exhibit distinct patterns in frequency, seasonality, and natural history.
  • Exacerbations are linked to accelerated lung function decline, increased disease severity, and higher mortality rates.
  • Differentiating between recurrent and relapsed exacerbations is important for clinical management.

Conclusions:

  • The epidemiology of COPD exacerbations is complex and multifactorial.
  • Effective management strategies should consider the frequency, timing, and impact of exacerbations.
  • Further research is needed to fully elucidate the relationship between exacerbations and long-term COPD outcomes.