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Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
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SGK1 kinase upregulates GLUT1 activity and plasma membrane expression

Monica Palmada1, Christoph Boehmer, Ahmad Akel

  • 1Institute of Physiology I, University of Tübingen, Germany.

Diabetes
|January 31, 2006
PubMed
Summary

Serum- and glucocorticoid-inducible kinase 1 (SGK1) enhances glucose transporter 1 (GLUT1) activity by increasing its presence in the cell membrane. This SGK1-mediated regulation of GLUT1 is independent of protein kinase B (PKB).

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