[Generalized arterial disease. Diagnostic assessment in general medical practice]
Related Experiment Video
Updated: Aug 13, 2026

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
1Arzt für Allgemeinmedizin, München.
Insights
Coronary arterial disease (CAD) is often systemic, yet only 30% of patients receive further vascular screening. Early detection of occlusive arterial disease (OAD) requires broader diagnostic approaches.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Preventive Cardiology
Context:
- Occlusive arterial disease (OAD) is a systemic condition impacting multiple vascular beds.
- Coronary arterial disease (CAD) frequently co-exists with peripheral and central arterial occlusions.
- Current diagnostic practices may underestimate the systemic nature of OAD.
Purpose:
- To evaluate the frequency of additional vascular diagnostic work-ups in patients primarily diagnosed with coronary arterial disease (CAD).
- To highlight the need for a more comprehensive approach to identifying systemic occlusive arterial disease (OAD).
Summary:
- A study examined 40 patients with primary CAD in a general practice setting.
- Only 30% of these patients underwent screening for additional peripheral or cerebral arterial occlusive sites.
- Clinical assessment alone often lacks sufficient sensitivity and specificity for detecting systemic OAD.
Impact:
- Suggests a need for increased awareness and implementation of systemic OAD screening in primary care.
- Recommends the integration of non-invasive screening methods, such as ultrasound, into routine office practice for high-risk patients.
- Emphasizes the importance of a global approach to prophylactic measures for occlusive arterial disease (OAD).
Problem:
Primary and secondary prophylactic measures can be effective only if they are global in nature. In this connection, occlusive arterial disease (OAD) must be considered to be a systemic disease, and the striking coincidence of peripheral, coronary and central occlusive sites must receive greater attention.
Study:
Examination of frequency of an additional peripheral or cerebral vascular diagnostic work-up in 40 nonselected patients with primary CHD in a general practice.
Results:
From a random sample of a group of patients from a general practitioner's office with the primary diagnosis of coronary arterial disease (CAD), it can be seen that in only 30 percent of the patients was a search for other sites of occlusion (peripheral, central) undertaken, irrespective of the underlying disease.
Conclusions:
For various reasons, in these patients, case history and the findings at physical examination often failed to provide adequate sensitivity and specificity, so that screening for high-risk patients using non-invasive methods (e.g. ultrasound) would be desirable also in the doctor's office.
Related Concept Videos
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Acute Coronary Syndrome III: Diagnostic Studies
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Aneurysm II: Clinical Manifestations and Diagnostic Studies

