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03:24
A Catheter-Related Candida albicans Infection Model in Mouse
Published on: March 22, 2024
Candida colonization in intensive care unit patients' urine
Xisto Sena Passos1, Werther Souza Sales, Patrícia Jackeline Maciel
1Universidade Paulista, Goiânia, GO, Brazil.
Memorias Do Instituto Oswaldo Cruz
|January 31, 2006
Summary
Antibiotic therapy and urinary catheters are key factors for candiduria in intensive care unit (ICU) patients. Surveillance is crucial to reduce these hospital-acquired infections.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Critical Care Medicine
Background:
- Candiduria, the presence of Candida yeasts in urine, is a significant concern in intensive care units (ICUs).
- Identifying predisposing factors is essential for preventing and managing candiduria, a potential indicator of systemic infection.
Purpose of the Study:
- To identify predisposing factors for candiduria in intensive care unit (ICU) patients.
- To determine the prevalence of different Candida species causing candiduria in this population.
Main Methods:
- Prospective study involving 153 ICU patients over one year.
- Urine samples collected via catheterization on admission and weekly.
- Data collected included patient demographics, antibiotic use, antifungal therapy, comorbidities, and length of hospital stay.
Main Results:
- Candiduria was detected in 68 patients.
- The most frequent predisposing factors were antibiotic therapy (100%) and indwelling urinary catheter use (92.6%).
- Candida albicans was the most common species (69.1%), followed by non-albicans Candida species.
Conclusions:
- Antibiotic therapy and urinary catheterization are major risk factors for candiduria in ICU patients.
- Increased isolation of Candida spp. correlated with longer ICU stays.
- Routine candiduria surveillance is recommended to reduce nosocomial infections in ICUs.
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