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Published on: April 13, 2018
Myocardial infarction and deep venous thrombosis in a young patient with Behçet disease
Meral Calgüneri1, Kudret Aydemir, M Akif Oztürk
1Rheumatology, Hacettepe University School of Medicine, Ankara, Turkey.
Insights
Behçet disease, a rare cause of heart attack, involves coronary arterial thrombosis and deep venous thrombosis. This case highlights the prothrombotic state in Behçet disease, emphasizing its impact on vascular health.
Area of Science:
- Cardiology
- Rheumatology
- Hematology
Background:
- Behçet disease (BD) is a chronic systemic vasculitis characterized by relapsing inflammatory episodes.
- Vascular manifestations in BD typically involve occlusive lesions, suggesting a prothrombotic state.
- Coronary artery involvement is an uncommon but serious complication of Behçet disease.
Observation:
- A 27-year-old male presented with myocardial infarction.
- The patient also exhibited deep venous thrombosis.
- Coronary arterial thrombosis was identified as the cause of myocardial infarction.
Findings:
- This case illustrates a rare presentation of Behçet disease with concurrent coronary arterial thrombosis and deep venous thrombosis.
- Pathologic hemostasis and the hypercoagulable state are key features contributing to thrombotic events in BD.
- The findings underscore the potential for severe cardiovascular complications in patients with Behçet disease.
Implications:
- Early recognition and management of thrombotic risk are crucial in Behçet disease patients.
- Understanding the prothrombotic mechanisms in BD can inform therapeutic strategies.
- This case highlights the importance of considering Behçet disease in young patients presenting with unexplained thrombosis.
Abstract:
Behçet disease (BD) is a chronic relapsing systemic vasculitic disorder affecting the arteries, veins, and vessels of any size. Vascular lesions in BD usually represent an occlusive nature suggesting a hypercoagulable/ prothrombotic state. Coronary arteries are rarely involved in BD. In this report, a 27-year-old male patient in whom myocardial infarction developed secondary to coronary arterial thrombosis together with deep venous thrombosis was presented. This is a review of the pathologic hemostasis and the prothrombotic state of BD.
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