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Published on: February 23, 2014
Childhood meningitis caused by enterococci and viridans streptococci
C T Koorevaar1, P G Scherpenzeel, H J Neijens
1Dept. of Pediatrics, Sophia Children's Hospital, Rotterdam, The Netherlands.
Abstract:
Selected clinical and laboratory parameters were studied respectively in patients with meningitis caused by enterococci and viridans streptococci in an academic children's hospital. During a nine-year period (1981-1989), enterococci or viridans streptococci were isolated from the cerobrospinal fluid (CSF) of 48 patients. In nine of these 48 patients, enterococci or viridans streptococci were the causative agents of meningitis. These nine children constituted 2.0% of 450 patients with bacterial meningitis in this period. All nine children suffered from underlying diseases; neurosurgical procedures were performed in six of these patients, of whom four had ventricular drains. A head trauma preceded the development of meningitis in another patient. Drainage of the lacrimal duct was associated with the development of meningitis in another patients. One child concurrently suffered from severe gastroenteritis. CSF leukocyte count and CSF protein levels were moderately elevated, whereas CSF glucose levels were either slightly decreased or within the normal range. Meningitis due to enterococci or viridans streptococci is seen predominantly in children under the age of one year. Predisposing factors, including neurosurgical procedures, head trauma and severe gastroenteritis, are usually present in these patients. The prognosis for recovery is generally good.
Insights
Meningitis in children caused by enterococci or viridans streptococci is rare, often linked to underlying conditions and procedures. Recovery is generally favorable for these pediatric meningitis cases.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Enterococci and viridans streptococci are uncommon causes of bacterial meningitis in children.
- These infections represent a small fraction of pediatric bacterial meningitis cases.
Purpose of the Study:
- To investigate clinical and laboratory features of meningitis caused by enterococci and viridans streptococci in pediatric patients.
- To identify predisposing factors and outcomes associated with these specific meningitis pathogens.
Main Methods:
- Retrospective analysis of pediatric patients diagnosed with meningitis.
- Isolation and identification of enterococci or viridans streptococci from cerebrospinal fluid (CSF).
- Review of clinical data, including patient history, underlying conditions, and laboratory CSF parameters.
Main Results:
- Nine cases of meningitis due to enterococci or viridans streptococci were identified over a nine-year period.
- These infections occurred predominantly in infants under one year old.
- Common predisposing factors included neurosurgical procedures, head trauma, and severe gastroenteritis.
- Cerebrospinal fluid analysis showed moderate elevation in leukocytes and protein, with normal or slightly decreased glucose levels.
Conclusions:
- Meningitis caused by enterococci or viridans streptococci in children is associated with significant underlying medical conditions and procedures.
- The prognosis for recovery in these cases is generally good despite the presence of predisposing factors.
- Early identification and management are crucial for favorable outcomes in pediatric meningitis.
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