Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Malignant adnexal neoplasms.

A Neil Crowson1, Cynthia M Magro, Martin C Mihm

  • 1Department of Dermatology, University of Oklahoma and Regional Medical Laboratory, St John Medical Center, Tulsa, OK 74114-4109, USA. ncrowson@sjmc.org

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
|February 1, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adenosine deaminase acting on RNA1 mutation in chilblain lupus treated with tofacitinib.

JAAD case reports·2026
Same author

Primary Cutaneous Coccidioidomycosis Presenting on the Leg of an Immunocompetent Patient: A Case Report.

Case reports in infectious diseases·2026
Same author

Diffuse Dermal Angiomatosis of the Breast Presenting as Diffuse Erythema Mimicking Inflammatory Breast Carcinoma in a Healthy Pregnant Patient.

The American Journal of dermatopathology·2026
Same author

The Evolution in the Cutaneous and Gastrointestinal Pathology of Pediatric Kohlmeier-Degos Disease Under Combined Modality Therapy.

The American Journal of dermatopathology·2025
Same author

A rare dermatologic condition: Insights from three cases of circumscribed acral hypokeratosis.

Clinics in dermatology·2025
Same author

Unicentric Subcutaneous Hyaline Vascular Castleman Disease With Concurrent Features of Calcifying Fibrous Tumor.

The American Journal of dermatopathology·2025
Same journal

Expanding the Spectrum of High-Risk Human Papilloma Virus (HPV)-Associated Glandular Neoplasms of the Anorectum.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same journal

Deep Learning for Differentiating Pulmonary Metastasis from Primary Lung Cancer Constructed on Frozen Sections for Intraoperative Diagnosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same journal

Margin Adequacy in Phyllodes Tumours Revisited: Reappraisal of the Evidence Base and Knowledge Gaps.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same journal

Genomic Characterization of Classic Adamantinoma, Osteofibrous Dysplasia, and Osteofibrous Dysplasia-like Adamantinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same journal

Immunophenotypic, Cytogenetic, and Molecular Characterization of NUP98-Rearranged Pediatric Myeloid Neoplasms.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same journal

Chromoanagenesis in Myelodysplastic Syndromes Is Associated With Highly Complex Karyotype, TP53 Disruption and Dismal Prognosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
See all related articles

This review details malignant cutaneous adnexal neoplasms, focusing on challenging pilosebaceous and sweat duct tumors. It aims to clarify classification of these diverse and complex skin neoplasms.

Area of Science:

  • Dermatopathology
  • Surgical Pathology
  • Oncology

Background:

  • Malignant cutaneous adnexal neoplasms represent a complex diagnostic challenge in dermatopathology.
  • Tumors of the pilosebaceous apparatus exhibit diverse differentiation patterns, involving hair bulb, follicular epithelium, and sebaceous glands.
  • Neoplasms of eccrine and apocrine glands present varied morphologies that often complicate precise classification.

Purpose of the Study:

  • To provide a detailed review of malignant neoplasms arising from the cutaneous adnexa.
  • To discuss the differential diagnosis of these malignant tumors, including their benign and prognostically indeterminate mimics.
  • To enhance the understanding and classification of complex adnexal neoplasms.

Main Methods:

  • Literature review of malignant cutaneous adnexal neoplasms.

Related Experiment Videos

  • Analysis of histopathological features and differentiation patterns.
  • Discussion of diagnostic criteria and classification challenges.

    • Main Results:

    • Malignant adnexal neoplasms exhibit diverse differentiation, including pilosebaceous and sweat gland components.
    • Complex proliferations with multilineal differentiation patterns are frequently encountered.
    • Morphological variability often challenges precise classification of eccrine and apocrine neoplasms.

    Conclusions:

    • Accurate classification of malignant cutaneous adnexal neoplasms requires detailed understanding of adnexal structures and differentiation.
    • Distinguishing malignant from benign and indeterminate lesions is crucial for patient prognosis.
    • Further research and standardized classification systems are needed for these challenging tumors.