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Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
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Nucleotide variability of HV-I in admixed population of the Brazilian Amazon Region

Ana Cecília Feio-Dos-Santos1, Bruno Maia Carvalho, Sidney Emanuel Batista dos Santos

  • 1Laboratório de Genética Humana e Médica, Departamento de Patologia, Universidade Federal do Pará, Belém, Pará, Brazil.

Forensic Science International
|February 2, 2006
PubMed

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
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