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Mohs micrographic surgery of the nail unit
1Department of Dermatology, College of Physicians and Surgeons of Columbia University, New York, New York.
Summary
Squamous cell carcinoma (SCC) of the nail unit is uncommon but can be fatal. Mohs micrographic surgery offers an ideal treatment for SCCs without bone involvement, improving patient outcomes.
Area of Science:
- Dermatology
- Oncology
- Surgical Pathology
Background:
- Nail unit malignancies are rare, with squamous cell carcinoma (SCC) being the most frequent.
- While often curable, SCC of the nail unit can lead to significant morbidity and mortality.
Purpose of the Study:
- To review the anatomy, histology, and prognostic factors of nail unit SCC.
- To evaluate the role of Mohs micrographic surgery in treating periungual and subungual SCCs.
- To discuss perioperative considerations for Mohs surgery in this context.
Main Methods:
- Literature review of nail unit SCC.
- Analysis of a personal case series.
- Review of surgical and histopathological data.
Main Results:
- Squamous cell carcinoma (SCC) is the predominant malignancy of the nail unit.
- Mohs micrographic surgery is highly effective for treating periungual and subungual SCCs that have not invaded bone.
- Understanding anatomical and histological features is crucial for successful surgical management.
Conclusions:
- Mohs micrographic surgery is the gold standard for selected nail unit SCCs.
- Comprehensive understanding of SCC and surgical techniques ensures optimal patient care.
- Early diagnosis and appropriate treatment are vital for managing this uncommon malignancy.