Imatinib as a potential antiresorptive therapy for bone disease

Andrea L Dewar1, Amanda N Farrugia, Mark R Condina

  • 1Division of Haematology, Institute of Medical and Veterinary Science, Frome Rd, Adelaide 5000, Australia.

Blood
|February 2, 2006
PubMed
Summary

Imatinib significantly reduces osteoclast activity and bone resorption at higher concentrations, suggesting its potential as an antiosteolytic therapy for bone diseases.

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