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Serum albumin and self-reported prevalence of stroke: a population-based, cross-sectional study
Arne T Høstmark1, Sissel E Tomten
1Department of Preventive Medicine and Epidemiology, University of Oslo, Norway. a.t.hostmark@medisin.uio.no
Background:
Since information about the association between serum albumin and risk of stroke is limited the purpose of the present paper was to re-investigate this relationship.
Design:
The study followed a cross-sectional design.
Methods:
In the cross-sectional Norwegian Oslo Health Study the concentration of serum albumin and blood pressure was determined in a random sample of 5071 men and women, 30-75 years of age. Logistic regression was used to study the association between the serum albumin concentration and self-reported prevalence of stroke. In the sample there were 122 subjects with a history of stroke and 4949 subjects without.
Results:
Low albumin (i.e. < or =47 versus >47 g/l) was associated with increased prevalence of self-reported stroke (odds ratio 1.83; 95% confidence interval, 1.20-2.78; P=0.005), after adjusting for age (< or =45 versus > or =59 years) and sex. Including smoking, blood pressure and length of education into the model did not have any major influence on the result.
Conclusion:
Low serum albumin is associated with increased prevalence of self-reported stroke.