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Related Experiment Videos

Maximal voluntary hyperpnoea increases blood lactate concentration during exercise.

Michael A Johnson1, Graham R Sharpe, Alison K McConnell

  • 1School of Biomedical and Natural Sciences, Nottingham Trent University, Nottingham, NG11 8NS, UK.

European Journal of Applied Physiology
|February 2, 2006
PubMed
Summary

Maximal isocapnic volitional hyperpnoea significantly increased blood lactate concentration during heavy endurance exercise. This suggests respiratory muscle work impacts systemic lactate levels, challenging previous assumptions in exercise physiology.

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Area of Science:

  • Exercise Physiology
  • Sports Science
  • Respiratory Physiology

Background:

  • Systemic lactate concentration is a key indicator of exercise intensity.
  • Ventilatory work during heavy endurance exercise has not been traditionally linked to systemic lactate changes.

Purpose of the Study:

  • To investigate the effect of maximal isocapnic volitional hyperpnoea on blood lactate concentration.
  • To determine if respiratory muscle work influences systemic lactate levels during steady-state exercise.

Main Methods:

  • Healthy males performed leg cycling at maximum lactate steady state (MLSS).
  • A control trial involved 30 minutes of exercise at MLSS.
  • An experimental trial superimposed maximal isocapnic volitional hyperpnoea from 20 to 28 minutes.

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Main Results:

  • Minute ventilation, oxygen uptake, and heart rate significantly increased during hyperpnoea.
  • Blood lactate concentration ([lac-]B) rose from 3.7 to 4.7 mmol/l during the experimental trial (20-30 min).
  • Partial pressure of carbon dioxide in venous blood increased during hyperpnoea.

Conclusions:

  • Respiratory muscle work during heavy exercise can influence systemic blood lactate concentration.
  • Altered lactate turnover in respiratory and/or locomotor muscles may explain the observed changes.
  • This finding challenges the notion that ventilatory work does not affect systemic lactate levels.