Related Experiment Video
Updated: Jun 10, 2026

High Throughput Fluorometric Technique for Assessment of Macrophage Phagocytosis and Actin Polymerization
Published on: November 27, 2014
[Disease entities caused by or involving the mononuclear phagocyte system]
Abstract:
In this review article we present an overview over the different functions of the mononuclear phagocyte system including different celltypes, i.e. monocyte, macrophage, epitheloid cells, Langhans cells and different dendritic cells. Further, diseases in which mononuclear macrophages are directly or indirectly involved are discussed. The review also discusses causes of monocytosis and monocytopenia along with non-malignant and malignant diseases, in which the mononuclear phagocyte has a crucial role.
Related Concept Videos
Cell-mediated Immune Responses
Inflammation
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Cells of the Innate Immune Response
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
Leishmaniasis

