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[Prognostic value of clinicopathologic factors in superficial bladder tumors: a retrospective analysis]
Soumaya Rammeh-Rommani1, Rachida Zermani, Béchir Zouari
1Service d'Anatomie et de Cytologie Pathologiques, Hôpital Charles Nicolle, Tunis.
Objective:
To study, through a series of superficial bladder tumors, the prognostic factors of recurrence and tumoral progression.
Materials And Methods:
This is a retrospective study of a series of 59 urothelial tumors of the bladder at stage pTa or pT1. The following parameters were considered: age, sex, treatment, stage and grade. The chi square test was used in search of a correlation between the different parameters and the course (recurrence and progress) of the disease. A multivariate analysis was undertaken by integrating factors correlated with the course.
Results:
Thirty two tumors (54 %) had recured versus 27 (46%) without recurrence. Eight tumors (25 %) progressed in grade and 4 (12,5 %) had become infiltrative. Age beyond 65 years, tumoral size > 3 cm and multifocality were predictive factors of recurrence with a relative risks of 2,36, 3,28 and 3,88 respectively. In a multivariate analysis, these factors remained significant with adjusted relatif risks respectively of 1,36, 1,6 and 1,7.