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Randomized controlled clinical trials on agents used for chemical plaque control
1Academic Center for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands. s.paraskevas@acta.nl
International Journal of Dental Hygiene
|February 3, 2006
Summary
Chemical agents in oral hygiene products effectively reduce plaque and gingival inflammation. This review analyzes clinical trials of agents used in toothpaste and mouthwash for long-term oral health benefits.
Area of Science:
- Oral Health
- Microbiology
- Preventive Dentistry
Background:
- Daily self-performed oral hygiene has limitations in effectively controlling plaque and gingival inflammation.
- Chemical agents offer a supplementary approach to enhance oral hygiene efficacy.
- Incorporation into dentifrice and mouth rinse formulations increases accessibility and compliance.
Purpose of the Study:
- To review randomized controlled clinical trials evaluating chemical agents for oral hygiene.
- To assess the long-term effects of these agents on plaque accumulation.
- To determine the impact on reducing gingival inflammation.
Main Methods:
- Systematic review of randomized controlled clinical trials (RCTs).
- Inclusion criteria: studies of >= 6 months duration.
- Focus on chemical agents in dentifrice or mouth rinse formulations.
Main Results:
- Chemical agents demonstrated significant reductions in plaque levels.
- Consistent improvements in reducing gingival inflammation were observed.
- Long-term use (>= 6 months) confirmed sustained efficacy.
Conclusions:
- Chemical agents incorporated into oral hygiene products are effective adjuncts.
- These agents provide a valuable strategy for managing plaque and gingivitis.
- Evidence supports their use for long-term oral health maintenance.
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