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A non-staining chlorhexidine mouthwash? Probably not: a study in vitro
1Division of Restorative Dentistry, Dental School, Bristol, UK. martin.addy@bristol.ac.uk
International Journal of Dental Hygiene
|February 3, 2006
Summary
New anti-discolouration system (ADS) rinses do not prevent tooth staining from chlorhexidine mouthwash. In vitro testing showed ADS rinses performed similarly to standard chlorhexidine rinses regarding staining potential.
Area of Science:
- Oral hygiene products
- Dental materials science
Background:
- Tooth staining is a common side effect of chlorhexidine mouth rinses.
- This staining results from the interaction between the antiseptic and dietary chromogens.
- A new anti-discolouration system (ADS) has been developed to mitigate this issue.
Purpose of the Study:
- To investigate the efficacy of two ADS rinses in preventing dietary chromogen binding.
- To compare the staining potential of ADS rinses against a positive control in vitro.
Main Methods:
- Acrylic specimens were exposed to saliva, chlorhexidine rinses (two ADS, one control), and tea.
- Staining was quantified by measuring optical density (OD) using a UV/visible spectrophotometer.
- The study determined the number of cycles until OD exceeded 2.0.
Main Results:
- All tested rinses, including the two ADS formulations and the positive control, reached an OD of >2.0 after 11 cycles.
- No statistically significant difference in staining was observed between the ADS rinses and the positive control rinse.
Conclusions:
- The tested ADS rinses demonstrated similar staining potential to established chlorhexidine rinses.
- It is predicted that these ADS rinses will exhibit comparable anti-plaque efficacy and staining propensity to existing chlorhexidine products in vivo.
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