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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Microbiology in diagnosis and treatment planning in periodontics
1Department of Oral Basic Sciences, Section Oral Microbiology, ACTA, Amsterdam, Van der Boechorststraat 7, 1081 BT Amsterdam, the Netherlands. AJ.van_Winkelhoff.omb.acta@med.vu.nl
Abstract:
Periodontitis is considered a multifactorial infectious disease in which bacteria play an essential role. It has become clear that not all patients with periodontitis harbour the same subgingival microflora, and so far, a limited number of species have been recognised as indicators for progression of periodontal breakdown. These findings are the basis for the use of clinical periodontal microbiology. Microbiological information can assist in diagnosis and treatment planning in periodontics, and is essential for the rational use of topical and systemic antimicrobial treatment. Different antimicrobial regimes have been proposed as adjuncts to mechanical periodontal treatment. This article reviews the current knowledge on periodontal microbiology, different techniques to test for marker bacteria and the use of antibiotics in the treatment of severe periodontitis.
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