Related Experiment Videos
Long-term changes in body composition after pancreatoduodenectomy.
F T Curran1, M A Stokes, G L Hill
1University Department of Surgery, Auckland Hospital, New Zealand.
Journal of the Royal College of Surgeons of Edinburgh
|February 1, 1991
Summary
This study on ampullary malignancy survivors found that Whipple
Area of Science:
- Surgical Oncology
- Gastroenterology
- Nutritional Science
Background:
- Ampullary malignancy poses significant nutritional challenges.
- Surgical intervention, like the Whipple procedure, impacts long-term body composition and nutrient absorption.
Purpose of the Study:
- To evaluate body protein and fat stores in long-term survivors of Whipple procedure for ampullary malignancy.
- To assess nutritional status, dietary intake, and fecal losses post-surgery.
Main Methods:
- Measurement of body protein and fat stores before and after Whipple procedure.
- Dietary assessment and measurement of fecal fat and protein losses at follow-up.
- Comparison of patient values with predicted well values.
Main Results:
- Patients maintained adequate caloric and protein intake post-surgery.
- Significant steatorrhoea (fat malabsorption) was observed, while protein losses were normal.
- Body weight and protein stores remained stable, but fat stores decreased significantly after surgery.
Conclusions:
- Curative Whipple procedure can prevent further weight loss in ampullary malignancy.
- Post-surgical weight gain is hindered by steatorrhoea, potentially linked to truncal vagotomy.
- Long-term nutritional management is crucial for patients undergoing Whipple procedure.