[Behçet's disease--difficulty in diagnostic and management]

Area of Science:

• Rheumatology
• Immunology
• Internal Medicine

Background:

• Behçet's disease is a rare systemic vasculitis of unknown etiology.
• It affects blood vessels of all sizes, leading to recurrent mucocutaneous and ocular issues.

Observation:

• A 31-year-old female presented with oral/genital ulcers, fever, knee pain, and erythema nodosum.
• Differential diagnoses were excluded to confirm Behçet's disease.

Findings:

• The patient experienced optimal improvement with a treatment regimen including azathioprine, cyclosporine A, and methylprednisolone.
• Individualized treatment is crucial, tailored to symptom presence and severity.

Implications:

• This case underscores the importance of accurate diagnosis of Behçet's disease, even when rare.
• Effective management involves a combination of immunosuppressive and anti-inflammatory agents.