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Updated: Jul 30, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
[Lemierre's syndrome and Mycoplasma pneumoniae]
M Rivero Marcotegui1, C Sánchez Rodríguez, S Cabal Soto
1Servicio de Medicina Interna, Clínica Ubarmin, Elcano. maria.rivero.marcotegui@cfnavarra.es
Abstract:
It has been suggested that a previous viral or bacterial pharyngitis may predispose to Lemierre's syndrome, an uncommon entity nowadays. A case of Lemierre's syndrome and co-infection with Mycoplasma pneumoniae is described, association published before in only 2 other cases. A 16-year-old girl with trombophlebitis of the left jugular vein, Fusobacterium necrophorum bacteremia and septic emboli in the lung requiring mechanical ventilation due to severe respiratory insufficiency. Despite early treatment with penicillin G and clindamycin, fever and part of pulmonary affectation persisted until that an antibiotic agent active against M. pneumoniae was instaurated, after its serological confirmation. The physicians should be easily recognized this disease because of its characteristic clinical findings, and co-infection with other organisms including M. pneumoniae, should be considered.
Insights
Lemierre
Area of Science:
- Infectious Diseases
- Microbiology
- Pulmonology
Background:
- Lemierre's syndrome, a rare thrombophlebitis of the neck, often follows pharyngitis.
- Prompt diagnosis and treatment are crucial for favorable outcomes.
Observation:
- A 16-year-old female presented with Lemierre's syndrome, characterized by jugular vein thrombophlebitis and septic lung emboli.
- The patient exhibited severe respiratory insufficiency requiring mechanical ventilation.
Findings:
- The patient had Fusobacterium necrophorum bacteremia and a concurrent Mycoplasma pneumoniae infection.
- Initial antibiotic therapy with penicillin G and clindamycin was insufficient until M. pneumoniae was targeted.
Implications:
- This case highlights the importance of considering M. pneumoniae co-infection in Lemierre's syndrome.
- Physicians should recognize characteristic clinical findings and consider polymicrobial infections in severe cases.
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